Concepedia

Initiation-selection Dynamics

Initiation-Selection Dynamics is a theoretical framework in cancer biology that delineates the temporal and mechanistic interplay between the initial mutagenic events driving tumorigenesis and the subsequent selective pressures shaping the expansion of malignant clones.

5

Publications

417

Citations

55

Authors

25

Institutions

Publications per year

2017–2026

1

Parents

Publications

5

NOTUM from Apc-mutant cells biases clonal competition to initiate cancer

Dustin J. Flanagan, Nalle Pentinmikko, Kalle Luopajärvi et al. · Nature · 2021 · 252 citations · Full text

, , +12

Phenobarbital as a promoter in the initiation/selection process of experimental rat hepatocarcinogenesis

M. Lans, J. de Geriache, H Taper et al. · Carcinogenesis · 1983 · 62 citations

, , +17

Reversal by ribo- and deoxyribonucleosides of dehydroepiandrosterone-induced inhibition of enzyme altered foci in the liver of rats subjected to the initiation-selection process of experimental carcinogenesis

Renato Garcea, Lucia Danio, Serenella Frassetto et al. · Carcinogenesis · 1988 · 47 citations

, , +8

Variety Creation, Growth and Selection Dynamics in the Early Phases of a Technological Transition: The Development of Alternative Transport Fuels in Sweden 1974-2004

Björn A. Sandén, Karl Jonasson · Chalmers Publication Library (Chalmers University of Technology) · 2005 · 42 citations

, , +14

Quantitative stereological studies of a 'selection' protocol of hepatocarcinogenesis following initiation in neonatal male and female rats

Yvonne P. Dragan · Carcinogenesis · 1997 · 14 citations · Full text

, , +12

1–5 of 5

Authors

55

  1. HT
    H Taper

    UCLouvain, Belgium

    1 publications · 62 citations

    1

    h-index

  2. BR
    Béatrice Romagnolo

    Inserm, France

    1 publications · 252 citations

    1

    h-index

  3. PV
    Paul V. Fish

    Pfizer (United Kingdom), United Kingdom

    1 publications · 252 citations

    1

    h-index

  4. MM
    Maria M. Simile

    University of Sassari, Italy

    1 publications · 47 citations

    1

    h-index

  5. RM
    Rosa M. Pascale

    University of Sassari, Italy

    1 publications · 47 citations

    1

    h-index

1–5 of 55

Institutions

25

  1. Beatson West of Scotland Cancer Centre

    Glasgow, United Kingdom

    1 h-index

    1 publications

    252 citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    1 h-index

    2 publications

    504 citations

  3. University of Helsinki

    Helsinki, Finland

    1 h-index

    9 publications

    2.3K citations

  4. Inserm

    Paris, France

    1 h-index

    2 publications

    504 citations

  5. University College London

    London, United Kingdom

    1 h-index

    2 publications

    504 citations

  6. The Francis Crick Institute

    London, United Kingdom

    1 h-index

    2 publications

    504 citations

  7. Helsinki Institute of Physics

    Helsinki, Finland

    1 h-index

    1 publications

    252 citations

  8. University of Glasgow

    Glasgow, United Kingdom

    1 h-index

    4 publications

    1K citations

1–8 of 25

Venues

  1. Carcinogenesis

    3 publications · 123 citations

    3

    h-index

  2. Nature

    1 publications · 252 citations

    1

    h-index

  3. Chalmers Publication Library (Chalmers University of Technology)

    Repository · 1 publications · 42 citations

    1

    h-index

1–3