Concepedia

Apoptosome Disassembly

Apoptosome Disassembly is a biochemical process characterized by the regulated dissociation of the apoptosome complex into its constituent proteins, distinguishing it from other apoptotic events by specifically terminating the complex’s activity in caspase activation.

19

Publications

2.1K

Citations

146

Authors

55

Institutions

Publications per year

2017–2026

3

Parents

Publications

19

Negative regulation of the Apaf-1 apoptosome by Hsp70

Ayman Saleh, Srinivasa M. Srinivasula, Levent Balkir et al. · Nature Cell Biology · 2000 · 820 citations

, , +14

Hsp27 Inhibits Cytochrome <i>c</i>-Mediated Caspase Activation by Sequestering Both Pro-caspase-3 and Cytochrome <i>c</i>

Caoimhín G. Concannon, S Orrenius, Afshin Samali · Gene Expression · 2001 · 221 citations · Full text

, , +15

Functional Interplay between Caspase Cleavage and Phosphorylation Sculpts the Apoptotic Proteome

Melissa M. Dix, Gabriel M. Simon, Chu Wang et al. · Cell · 2012 · 143 citations · Full text

, , +17

Three-dimensional Structure of a Double Apoptosome Formed by the Drosophila Apaf-1 Related Killer

Xinchao Yu, Lai Wang, Devrim Acehan et al. · Journal of Molecular Biology · 2005 · 132 citations

, , +15

Intracellular Nucleotides Act as Critical Prosurvival Factors by Binding to Cytochrome C and Inhibiting Apoptosome

Dhyan Chandra, Shawn B. Bratton, Maria D. Person et al. · Cell · 2006 · 128 citations · Full text

, , +17

1–5 of 19

Authors

146

  1. HO
    Howard O. Fearnhead

    Ollscoil na Gaillimhe – University of Galway, Ireland

    4 publications · 209 citations

    4

    h-index

  2. SB
    Shawn B. Bratton

    The University of Texas at Austin, United States

    2 publications · 253 citations

    2

    h-index

  3. AS
    Afshin Samali

    Ollscoil na Gaillimhe – University of Galway, Ireland

    2 publications · 238 citations

    2

    h-index

  4. ÁG
    Ángel G. Martín

    Institut d'Investigació Biomèdica de Girona, Spain

    2 publications · 164 citations

    2

    h-index

  5. DC
    Dhyan Chandra

    Roswell Park Comprehensive Cancer Center, United States

    2 publications · 178 citations

    2

    h-index

1–5 of 146

Institutions

55

  1. Ollscoil na Gaillimhe – University of Galway

    Galway, Ireland

    3 h-index

    12 publications

    838 citations

  2. Yonsei University

    Seoul, South Korea

    2 h-index

    9 publications

    272 citations

  3. Novartis (United States)

    New York, United States

    1 h-index

    1 publications

    112 citations

  4. Cold Spring Harbor Laboratory

    Cold Spring Harbor, United States

    1 h-index

    1 publications

    112 citations

  5. Medical Research Council

    London, United Kingdom

    1 h-index

    3 publications

    375 citations

  6. Sidney Kimmel Cancer Center

    Philadelphia, United States

    1 h-index

    3 publications

    2.5K citations

  7. Ospedale San Filippo Neri

    Rome, Italy

    1 h-index

    1 publications

    14 citations

  8. Texas A&M University

    College Station, United States

    1 h-index

    1 publications

    128 citations

1–8 of 55

Venues

  1. Cell Death and Differentiation

    CDD · 4 publications · 259 citations

    4

    h-index

  2. Biochemical and Biophysical Research Communications

    BBRC · 2 publications · 62 citations

    2

    h-index

  3. Cell

    2 publications · 271 citations

    2

    h-index

  4. Nature Cell Biology

    NCB · 2 publications · 884 citations

    2

    h-index

  5. APOPTOSIS

    2 publications · 31 citations

    2

    h-index

1–5