Srinivasa M. Srinivasula

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

Peng Li, Deepak Nijhawan, I. Imawati Budihardjo et al. · Cell · 1997 · 7.2K citations · Full text

Protein Function, Signal Transduction, Biochemistry +12

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, Fábio Camargo Abdalla, Hagai Abeliovich et al. · Autophagy · 2012 · 4K citations · Full text

Mitophagy, Particular Autophagy Assays, Immunology +19

Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells

Jialun Wang, Dongxiang Liu, Zhijia Zhang et al. · Proceedings of the National Academy of Sciences · 2000 · 1.2K citations · Full text

Autoactivation of Procaspase-9 by Apaf-1-Mediated Oligomerization

Srinivasa M. Srinivasula, Manzoor Ahmad, Teresa Fernandes‐Alnemri et al. · Molecular Cell · 1998 · 1.1K citations · Full text

Protein Function, Signal Transduction, Protein Expression +4

A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis

Srinivasa M. Srinivasula, R.P. Hegde, Ayman Saleh et al. · Nature · 2001 · 994 citations

Signal Transduction, Autoimmune Disease, Signaling Pathway +11