Concepedia

A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis

Srinivasa M. Srinivasula, R.P. Hegde, Ayman Saleh, Pinaki Datta, Eric N. Shiozaki, Jijie Chai, Ryung‐Ah Lee, Paul D. Robbins, Teresa Fernandes‐Alnemri, Yigong Shi,

Nature · 2001 · 1K citations · 13 references

DOI

Concepts

References

13

Smac, a Mitochondrial Protein that Promotes Cytochrome c–Dependent Caspase Activation by Eliminating IAP Inhibition

Chunying Du, Min Fang, Yucheng Li et al. · Cell · 2000 · 3.5K citations · Full text

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Identification of DIABLO, a Mammalian Protein that Promotes Apoptosis by Binding to and Antagonizing IAP Proteins

Anne M. Verhagen, Paul G. Ekert, Miha Pakusch et al. · Cell · 2000 · 2.3K citations · Full text

, , +14

Autoactivation of Procaspase-9 by Apaf-1-Mediated Oligomerization

Srinivasa M. Srinivasula, Manzoor Ahmad, Teresa Fernandes‐Alnemri et al. · Molecular Cell · 1998 · 1.1K citations · Full text

, , +12

Structural and biochemical basis of apoptotic activation by Smac/DIABLO

Jijie Chai, Chunying Du, Jiawei Wu et al. · Nature · 2000 · 857 citations

, , +14

Structural basis of IAP recognition by Smac/DIABLO

Geng Wu, Jijie Chai, Tomeka Suber et al. · Nature · 2000 · 856 citations

, , +12