Concepedia

Allosteric Specificity

Allosteric Specificity is a theoretical construct in enzymology that characterizes the selective modulation of an enzyme's catalytic activity at one site through the binding of an effector molecule at a distinct, spatially separated allosteric site, thereby conferring regulatory specificity beyond the active site's substrate recognition.

75

Publications

4.9K

Citations

371

Authors

133

Institutions

Publications per year

2017–2026

13

Parents

Publications

75

An mRNA structure that controls gene expression by binding FMN

Wade C. Winkler, Smadar Cohen‐Chalamish, Ronald R. Breaker · Proceedings of the National Academy of Sciences · 2002 · 712 citations · Full text

, , +17

Pan-KRAS inhibitor disables oncogenic signalling and tumour growth

Dong-Sung Kim, Lorenz Herdeis, Dorothea Rudolph et al. · Nature · 2023 · 497 citations · Full text

, , +17

How allosteric control of <i>Staphylococcus aureus</i> penicillin binding protein 2a enables methicillin resistance and physiological function

Lisandro H. Otero, A. Rojas-Altuve, Leticia I. Llarrull et al. · Proceedings of the National Academy of Sciences · 2013 · 269 citations · Full text

, , +17

Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism

K. Thangavelu, Catherine Pan, T. Karlberg et al. · Proceedings of the National Academy of Sciences · 2012 · 202 citations · Full text

, , +16

Seaweeds for umami flavour in the New Nordic Cuisine

Ole G. Mouritsen, Lars Williams, Rasmus Bjerregaard et al. · Flavour · 2012 · 175 citations · Full text

, , +12

1–5 of 75

Authors

371

  1. RA
    Roy A. Jensen

    University of Florida, United States

    3 publications · 82 citations

    3

    h-index

  2. RN
    Ruth Nussinov

    Tel Aviv University, Israel

    2 publications · 150 citations

    2

    h-index

  3. JS
    J. Sivaraman

    National University of Singapore, Singapore

    2 publications · 248 citations

    2

    h-index

  4. IW
    Ingrid W. Caras

    University of California, San Francisco, United States

    2 publications · 61 citations

    2

    h-index

  5. BC
    Boon Chuan Low

    National University of Singapore, Singapore

    2 publications · 248 citations

    2

    h-index

1–5 of 371

Institutions

133

  1. Baylor College of Medicine

    Houston, United States

    4 h-index

    10 publications

    331 citations

  2. National Institutes of Health

    Bethesda, United States

    4 h-index

    12 publications

    548 citations

  3. Michigan State University

    East Lansing, United States

    3 h-index

    10 publications

    212 citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    3 h-index

    5 publications

    238 citations

  5. Memorial Sloan Kettering Cancer Center

    New York, United States

    2 h-index

    13 publications

    6.1K citations

  6. Universidad Nacional Autónoma de México

    Mexico City, Mexico

    2 h-index

    6 publications

    70 citations

  7. University of California, San Francisco

    San Francisco, United States

    2 h-index

    5 publications

    165 citations

  8. University of California San Diego

    San Diego, United States

    2 h-index

    2 publications

    133 citations

1–8 of 133

Venues

  1. Journal of Biological Chemistry

    JBC · 10 publications · 424 citations

    10

    h-index

  2. Biochemistry

    8 publications · 466 citations

    8

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 5 publications · 1.4K citations

    5

    h-index

  4. Archives of Biochemistry and Biophysics

    ABB · 4 publications · 71 citations

    4

    h-index

  5. eLife

    3 publications · 163 citations

    3

    h-index

1–5