Dong-Sung Kim

Rapid non-uniform adaptation to conformation-specific KRAS(G12C) inhibition

Jenny Y. Xue, Yulei Zhao, Jordan Aronowitz et al. · Nature · 2020 · 522 citations · Full text

Signal Transduction, Biochemistry, G Protein-coupled Receptor +7

Pan-KRAS inhibitor disables oncogenic signalling and tumour growth

Dong-Sung Kim, Lorenz Herdeis, Dorothea Rudolph et al. · Nature · 2023 · 448 citations · Full text

Diverse alterations associated with resistance to KRAS(G12C) inhibition

Yulei Zhao, Yonina R. Murciano‐Goroff, Jenny Y. Xue et al. · Nature · 2021 · 405 citations · Full text

Molecular Pharmacology, Signal Transduction, Medicine +6

Quantitative determinants of aerobic glycolysis identify flux through the enzyme GAPDH as a limiting step

Alexander A. Shestov, Xiaojing Liu, Zheng Ser et al. · eLife · 2014 · 301 citations · Full text

Limiting Step, Upper Glycolysis, Glycobiology +19

The ALS/FTLD associated protein C9orf72 associates with SMCR8 and WDR41 to regulate the autophagy-lysosome pathway

Peter M. Sullivan, Xiaolai Zhou, Adam M. Robins et al. · Acta Neuropathologica Communications · 2016 · 286 citations · Full text

Mitophagy, Genetics, Cell Death +17