Concepedia

Lorenz Herdeis

LH

Statistics

Publications

3

Citations

592

H-Index

3

Active since

2022

Affiliations

Boehringer Ingelheim (Austria)(Current)

Lorenz Herdeis is an author at Boehringer Ingelheim (Austria) specializing in molecular oncology, kras inhibitors, and ligand binding.

Publications per year

2022–2024

3

Publications

3

Pan-KRAS inhibitor disables oncogenic signalling and tumour growth

Dong-Sung Kim, Lorenz Herdeis, Dorothea Rudolph et al. · Nature · 2023 · 497 citations · Full text

Medicine, Oncology, Pharmacology +17

Fragment Optimization of Reversible Binding to the Switch II Pocket on KRAS Leads to a Potent, In Vivo Active KRAS <sup>G12C</sup> Inhibitor

Joachim Bröker, Alex G. Waterson, Chris A. Smethurst et al. · Journal of Medicinal Chemistry · 2022 · 81 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +16

Abstract 3317: KRASmulti inhibitor BI 3706674 shows efficacy in KRAS-driven preclinical models of cancer that supports clinical testing in patients with tumors harbouring KRASG12V mutations and KRAS wild-type amplifications

Antonio Tedeschi, David H. Peng, Fiorella Schischlik et al. · Cancer Research · 2024 · 14 citations

Medicine, Molecular Biology, Oncology +13

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