Concepedia

Chris A. Smethurst

CA

Statistics

Publications

3

Citations

117

H-Index

3

Active since

2010

Affiliations

GlaxoSmithKline (United Kingdom)(Current)

Chris A. Smethurst is an author at GlaxoSmithKline (United Kingdom) specializing in medicine, drug discovery, and pharmacology.

Top concepts

Publications per year

2010–2022

3

Publications

3

Fragment Optimization of Reversible Binding to the Switch II Pocket on KRAS Leads to a Potent, In Vivo Active KRAS <sup>G12C</sup> Inhibitor

Joachim Bröker, Alex G. Waterson, Chris A. Smethurst et al. · Journal of Medicinal Chemistry · 2022 · 72 citations · Full text

Identification of a sulfonamide series of CCR2 antagonists

Simon Peace, Joanne Philp, Carl Brooks et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 35 citations · Full text

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Discovery of Tetrahydropyrazolopyridine as Sphingosine 1-Phosphate Receptor 3 (S1P<sub>3</sub>)-Sparing S1P<sub>1</sub> Agonists Active at Low Oral Doses

Emmanuel H. Demont, James M. Bailey, Rino A. Bit et al. · Journal of Medicinal Chemistry · 2016 · 10 citations · Full text

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