Joanne Philp

The discovery of GSK221149A: A potent and selective oxytocin antagonist

John Liddle, Michael Allen, Alan D. Borthwick et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 90 citations · Full text

Selective Oxytocin, Medicinal Chemistry, Biochemistry +9

Inhibition of the Cardiomyocyte-Specific Kinase TNNI3K Limits Oxidative Stress, Injury, and Adverse Remodeling in the Ischemic Heart

Ronald J. Vagnozzi, Gregory J. Gatto, Lara S. Kallander et al. · Science Translational Medicine · 2013 · 70 citations · Full text

Identification of Purines and 7-Deazapurines as Potent and Selective Type I Inhibitors of Troponin I-Interacting Kinase (TNNI3K)

Brian G. Lawhorn, Joanne Philp, Yongdong Zhao et al. · Journal of Medicinal Chemistry · 2015 · 46 citations · Full text

Medicinal Chemistry, Pharmaceutical Chemistry, Signal Transduction +14

Identification of a sulfonamide series of CCR2 antagonists

Simon Peace, Joanne Philp, Carl Brooks et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 35 citations · Full text

Medicine, Sulfonamide Series, Mechanism Of Action +4

4,6-Diaminopyrimidines as Highly Preferred Troponin I-Interacting Kinase (TNNI3K) Inhibitors

Joanne Philp, Brian G. Lawhorn, Alan P. Graves et al. · Journal of Medicinal Chemistry · 2018 · 25 citations · Full text

Molecular Docking, Medicinal Chemistry, Heart Failure +10