Concepedia

Adaptive Metabolic Reprogramming

Adaptive Metabolic Reprogramming is a metabolic regulatory mechanism that dynamically alters flux through the pentose phosphate pathway in response to cellular redox and biosynthetic demands, distinguishing it from constitutive metabolic pathways by its context-sensitive activation and stoichiometric flexibility.

116

Publications

8K

Citations

1K

Authors

375

Institutions

Publications per year

2017–2026

80

Parents

Publications

116

Regulation of Oxygen Homeostasis by Hypoxia-Inducible Factor 1

Gregg L. Semenza · Physiology · 2009 · 926 citations

, , +15

Metabolic reprogramming of natural killer cells in obesity limits antitumor responses

Xavier Michelet, Lydia Dyck, Andrew E. Hogan et al. · Nature Immunology · 2018 · 610 citations

, , +16

Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism

Douglas E. Biancur, João A. Paulo, Beata Małachowska et al. · Nature Communications · 2017 · 316 citations · Full text

, , +17

Metabolic plasticity underpins innate and acquired resistance to LDHA inhibition

Aaron Boudreau, Hans E. Purkey, A. Hitz et al. · Nature Chemical Biology · 2016 · 268 citations · Full text

, , +13

Reserve Flux Capacity in the Pentose Phosphate Pathway Enables Escherichia coli's Rapid Response to Oxidative Stress

Dimitris Christodoulou, Hannes Link, Tobias Fuhrer et al. · Cell Systems · 2018 · 225 citations · Full text

, , +15

1–5 of 116

Authors

1K

  1. OF
    Oliver Fiehn

    University of California, Davis, United States

    2 publications · 120 citations

    2

    h-index

  2. YL
    Yang Li

    Radboud University Nijmegen, Netherlands

    2 publications · 128 citations

    2

    h-index

  3. DC
    Dario C. Altieri

    The Wistar Institute, United States

    2 publications · 127 citations

    2

    h-index

  4. GL
    Gregg L. Semenza

    Johns Hopkins University, United States

    2 publications · 1K citations

    2

    h-index

  5. CA
    Christopher A. Bradfield

    University of Wisconsin–Madison, United States

    1 publications · 217 citations

    1

    h-index

1–5 of 1K

Institutions

375

  1. Harvard University

    Cambridge, United States

    8 h-index

    26 publications

    6.2K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    6 h-index

    13 publications

    525 citations

  3. Duke University

    Durham, United States

    4 h-index

    14 publications

    406 citations

  4. Johns Hopkins University

    Baltimore, United States

    4 h-index

    10 publications

    1.3K citations

  5. Washington University in St. Louis

    St Louis, United States

    4 h-index

    12 publications

    648 citations

  6. Sun Yat-sen University

    Guangzhou, China

    3 h-index

    26 publications

    964 citations

  7. Center for Cancer Research

    Bethesda, United States

    3 h-index

    25 publications

    2.1K citations

  8. The Wistar Institute

    Philadelphia, United States

    3 h-index

    19 publications

    1.9K citations

1–8 of 375

Venues

  1. Nature Communications

    5 publications · 588 citations

    5

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 166 citations

    3

    h-index

  3. JCI Insight

    2 publications · 108 citations

    2

    h-index

  4. Metabolic Engineering

    2 publications · 61 citations

    2

    h-index

  5. Autophagy

    2 publications · 91 citations

    2

    h-index

1–5