Aaron Boudreau

Metabolite profiling stratifies pancreatic ductal adenocarcinomas into subtypes with distinct sensitivities to metabolic inhibitors

Anneleen Daemen, David Peterson, Nisebita Sahu et al. · Proceedings of the National Academy of Sciences · 2015 · 418 citations · Full text

Medicine, Biochemistry, Oncology +17

Metabolic plasticity underpins innate and acquired resistance to LDHA inhibition

Aaron Boudreau, Hans E. Purkey, A. Hitz et al. · Nature Chemical Biology · 2016 · 268 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Gene Co-Expression Modules as Clinically Relevant Hallmarks of Breast Cancer Diversity

Denise M. Wolf, Marc E. Lenburg, Christina Yau et al. · PLoS ONE · 2014 · 144 citations · Full text

Medicine, Cancer Biology, Oncology +17

Metabolic and transcriptional profiling reveals pyruvate dehydrogenase kinase 4 as a mediator of epithelial-mesenchymal transition and drug resistance in tumor cells

Yuting Sun, Anneleen Daemen, Georgia Hatzivassiliou et al. · Cancer & Metabolism · 2014 · 138 citations · Full text

Medicine, Oncology, Pharmacology +17

Splicing program of human MENA produces a previously undescribed isoform associated with invasive, mesenchymal-like breast tumors

Francesca Di Modugno, Pierluigi Iapicca, Aaron Boudreau et al. · Proceedings of the National Academy of Sciences · 2012 · 116 citations · Full text

Medicine, Molecular Biology, Oncology +16