Concepedia

Hans E. Purkey

HE

Statistics

Publications

43

Citations

3.2K

H-Index

30

Active since

1998

Affiliations

Scripps Research Institute(Current)

WuXi AppTec (China)

Sunesis (United States)

Texas A&M University

Charles River Laboratories (United Kingdom)

Hans E. Purkey is an author at Scripps Research Institute specializing in pharmacology, drug discovery, and medicinal chemistry.

ORCID

Publications per year

1998–2023

43

Publications

43

Discovery of a Potent and Selective BCL-X <sub>L</sub> Inhibitor with <i>in Vivo</i> Activity

Zhi‐Fu Tao, Lisa Hasvold, Le Wang et al. · ACS Medicinal Chemistry Letters · 2014 · 331 citations · Full text

, , +10

Metabolic plasticity underpins innate and acquired resistance to LDHA inhibition

Aaron Boudreau, Hans E. Purkey, A. Hitz et al. · Nature Chemical Biology · 2016 · 268 citations · Full text

, , +13

Benzoxazoles as Transthyretin Amyloid Fibril Inhibitors: Synthesis, Evaluation, and Mechanism of Action

Hossein Razavi, S.K. Palaninathan, Evan T. Powers et al. · Angewandte Chemie International Edition · 2003 · 232 citations

, , +16

Inhibiting transthyretin conformational changes that lead to amyloid fibril formation

Scott Peterson, Thomas Klabunde, Hilal A. Lashuel et al. · Proceedings of the National Academy of Sciences · 1998 · 205 citations · Full text

, , +17

Structural basis for dual-mode inhibition of the ABC transporter MsbA

Hoangdung Ho, Anh Miu, Mary Kate Alexander et al. · Nature · 2018 · 176 citations

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