Hilal A. Lashuel

Amyloid pores from pathogenic mutations

Hilal A. Lashuel, Dean M. Hartley, Benjamin M. Petre et al. · Nature · 2002 · 1.3K citations · Full text

Alzheimer's Disease, Medicine, Pathogenesis +5

α-Synuclein, Especially the Parkinson's Disease-associated Mutants, Forms Pore-like Annular and Tubular Protofibrils

Hilal A. Lashuel, Benjamin M. Petre, Joseph S. Wall et al. · Journal of Molecular Biology · 2002 · 804 citations · Full text

Neurodegenerative Diseases, Forms Pore-like Annular, Molecular Biology +6

The UCH-L1 Gene Encodes Two Opposing Enzymatic Activities that Affect α-Synuclein Degradation and Parkinson's Disease Susceptibility

Yichin Liu, Lara Fallon, Hilal A. Lashuel et al. · Cell · 2002 · 787 citations · Full text

Disease Susceptibility, Neurodegenerative Diseases, Molecular Neuroscience +12

The process of Lewy body formation, rather than simply α-synuclein fibrillization, is one of the major drivers of neurodegeneration

Anne‐Laure Mahul‐Mellier, Johannes Burtscher, Niran Maharjan et al. · Proceedings of the National Academy of Sciences · 2020 · 712 citations · Full text

α-Synuclein in Central Nervous System and from Erythrocytes, Mammalian Cells, and Escherichia coli Exists Predominantly as Disordered Monomer

Bruno Fauvet, Martial Mbefo, Mohamed-Bilal Fares et al. · Journal of Biological Chemistry · 2012 · 556 citations · Full text

Neurodegenerative Diseases, Molecular Neuroscience, Neurobiology Of Disease +15