João A. Paulo

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, João A. Paulo et al. · Nature · 2017 · 1.5K citations · Full text

The BioPlex Network: A Systematic Exploration of the Human Interactome

Edward L. Huttlin, Lily Ting, Raphael J. Bruckner et al. · Cell · 2015 · 1.5K citations · Full text

Bioinformatics, Engineering, Interactomics +11

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I

Keisuke Yamamoto, Anthony Venida, Julian Yano et al. · Nature · 2020 · 1.1K citations · Full text

Cell Autophagy, Immune Evasion, Pancreatic Cancer +7

Dual proteome-scale networks reveal cell-specific remodeling of the human interactome

Edward L. Huttlin, Raphael J. Bruckner, José Navarrete-Perea et al. · Cell · 2021 · 947 citations · Full text

Signal Transduction, Dual Proteome-scale Networks, Cell Division +12

The PINK1-PARKIN Mitochondrial Ubiquitylation Pathway Drives a Program of OPTN/NDP52 Recruitment and TBK1 Activation to Promote Mitophagy

Jin‐Mi Heo, Alban Ordureau, João A. Paulo et al. · Molecular Cell · 2015 · 849 citations · Full text

Cell Autophagy, Mitophagy, Optn/ndp52 Recruitment +9