Malini Menon

Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance

Stephen J. Pettitt, Dragomir B. Krastev, Inger Brandsma et al. · Nature Communications · 2018 · 435 citations · Full text

Small Molecule Inhibitors of the Neuropilin-1 Vascular Endothelial Growth Factor A (VEGF-A) Interaction

Ashley Jarvis, C.K. Allerston, Haiyan Jia et al. · Journal of Medicinal Chemistry · 2010 · 194 citations · Full text

Small Molecule Inhibitors, Endothelial Cells, Small Molecule Design +18

E-Cadherin/ROS1 Inhibitor Synthetic Lethality in Breast Cancer

Ilirjana Bajrami, Rebecca Marlow, Marieke van de Ven et al. · Cancer Discovery · 2018 · 129 citations · Full text

Modeling Therapy Resistance in <i>BRCA1/2</i> -Mutant Cancers

Amy Dréan, Chris T. Williamson, Rachel Brough et al. · Molecular Cancer Therapeutics · 2017 · 86 citations · Full text

Hi-JAK-ing the ubiquitin system: The design and physicochemical optimisation of JAK PROTACs

Rishi R. Shah, Joanna M. Redmond, Andrei Mihut et al. · Bioorganic & Medicinal Chemistry · 2020 · 66 citations · Full text

Protein Chemistry, Engineering, Biochemistry +10