Inger Brandsma

The shieldin complex mediates 53BP1-dependent DNA repair

Sylvie M. Noordermeer, Salomé Adam, Dheva Setiaputra et al. · Nature · 2018 · 635 citations · Full text

Chromatin, Genome Instability, Chromatin Remodeling +4

REV7 counteracts DNA double-strand break resection and affects PARP inhibition

Guotai Xu, J. Ross Chapman, Inger Brandsma et al. · Nature · 2015 · 583 citations · Full text

Chromatin, Genome Instability, Parp Inhibition +6

Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance

Stephen J. Pettitt, Dragomir B. Krastev, Inger Brandsma et al. · Nature Communications · 2018 · 435 citations · Full text

Pathway choice in DNA double strand break repair: observations of a balancing act

Inger Brandsma, Dik C. van Gent · Genome Integrity · 2012 · 294 citations · Full text

Dna Damage, Numerous Assays, Genetics +19

BRCA1185delAG tumors may acquire therapy resistance through expression of RING-less BRCA1

Rinske Drost, Kiranjit K. Dhillon, Hanneke van der Gulden et al. · Journal of Clinical Investigation · 2016 · 137 citations · Full text

Breast Oncology, Brca1185stop Mutations, Brca1 Protein +18