Dragomir B. Krastev

The shieldin complex mediates 53BP1-dependent DNA repair

Sylvie M. Noordermeer, Salomé Adam, Dheva Setiaputra et al. · Nature · 2018 · 660 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +11

Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance

Stephen J. Pettitt, Dragomir B. Krastev, Inger Brandsma et al. · Nature Communications · 2018 · 447 citations · Full text

Medicine, Molecular Biology, Oncology +17

Structural basis for allosteric PARP-1 retention on DNA breaks

Levani Zandarashvili, Marie-France Langelier, Uday Kiran Velagapudi et al. · Science · 2020 · 331 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

PARP inhibition enhances tumor cell–intrinsic immunity in ERCC1-deficient non–small cell lung cancer

Roman M. Chabanon, Gareth Muirhead, Dragomir B. Krastev et al. · Journal of Clinical Investigation · 2018 · 324 citations · Full text

Life Sciences, Immunology, Oncology +17

A Genome-Scale DNA Repair RNAi Screen Identifies SPG48 as a Novel Gene Associated with Hereditary Spastic Paraplegia

Mikołaj Słabicki, Mirko Theis, Dragomir B. Krastev et al. · PLoS Biology · 2010 · 195 citations · Full text

Life Sciences, Genetics, Molecular Biology +13