Marie-France Langelier

Structural Basis for DNA Damage–Dependent Poly(ADP-ribosyl)ation by Human PARP-1

Marie-France Langelier, Jamie L. Planck, Swati Roy et al. · Science · 2012 · 659 citations

Crystal Structure, Biochemistry, Protein Assembly +11

PARP-1 Activation Requires Local Unfolding of an Autoinhibitory Domain

Jennine M. Dawicki-McKenna, Marie-France Langelier, Jamie E. DeNizio et al. · Molecular Cell · 2015 · 339 citations · Full text

Protein Function, Signal Transduction, Signal Recognition +4

Structural Basis of Detection and Signaling of DNA Single-Strand Breaks by Human PARP-1

Sebastian Eustermann, Wing-Fung Wu, Marie-France Langelier et al. · Molecular Cell · 2015 · 320 citations · Full text

Structural basis for allosteric PARP-1 retention on DNA breaks

Levani Zandarashvili, Marie-France Langelier, Uday Kiran Velagapudi et al. · Science · 2020 · 315 citations · Full text

PARP-2 and PARP-3 are selectively activated by 5′ phosphorylated DNA breaks through an allosteric regulatory mechanism shared with PARP-1

Marie-France Langelier, Amanda A. Riccio, John M. Pascal · Nucleic Acids Research · 2014 · 271 citations · Full text