C.K. Allerston

Small Molecule Inhibitors of the Neuropilin-1 Vascular Endothelial Growth Factor A (VEGF-A) Interaction

Ashley Jarvis, C.K. Allerston, Haiyan Jia et al. · Journal of Medicinal Chemistry · 2010 · 194 citations · Full text

Small Molecule Inhibitors, Endothelial Cells, Small Molecule Design +18

Crystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changes

J.A. Newman, P. Savitsky, C.K. Allerston et al. · Nucleic Acids Research · 2015 · 91 citations · Full text

Crystal Structure, Hrdc Domain, Protein Assembly +16

Pirtobrutinib preclinical characterization: a highly selective, non-covalent (reversible) BTK inhibitor

Eliana B Gómez, Kevin Ebata, Hetal S Randeria et al. · Blood · 2023 · 84 citations · Full text

Crystal Structures of the Catalytic Domain of Human Soluble Guanylate Cyclase

C.K. Allerston, F. von Delft, O. Gileadi · PLoS ONE · 2013 · 81 citations · Full text

Catalytic Domain, Cellular Enzymology, Protein Assembly +13

Structural characterization of human Vaccinia-Related Kinases (VRK) bound to small-molecule inhibitors identifies different P-loop conformations

Rafael M. Couñago, C.K. Allerston, P. Savitsky et al. · Scientific Reports · 2017 · 59 citations · Full text