C.K. Allerston

Small Molecule Inhibitors of the Neuropilin-1 Vascular Endothelial Growth Factor A (VEGF-A) Interaction

Ashley Jarvis, C.K. Allerston, Haiyan Jia et al. · Journal of Medicinal Chemistry · 2010 · 198 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Crystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changes

J.A. Newman, P. Savitsky, C.K. Allerston et al. · Nucleic Acids Research · 2015 · 92 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

Pirtobrutinib preclinical characterization: a highly selective, non-covalent (reversible) BTK inhibitor

Eliana B Gómez, Kevin Ebata, Hetal S Randeria et al. · Blood · 2023 · 88 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Crystal Structures of the Catalytic Domain of Human Soluble Guanylate Cyclase

C.K. Allerston, F. von Delft, O. Gileadi · PLoS ONE · 2013 · 81 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Structural characterization of human Vaccinia-Related Kinases (VRK) bound to small-molecule inhibitors identifies different P-loop conformations

Rafael M. Couñago, C.K. Allerston, P. Savitsky et al. · Scientific Reports · 2017 · 60 citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Biology +7