Jason Phan

Discovery of Small Molecules that Bind to K‐Ras and Inhibit Sos‐Mediated Activation

Qi Sun, Jason P. Burke, Jason Phan et al. · Angewandte Chemie International Edition · 2012 · 495 citations

Drug Target, Nmr Spectroscopy, Molecular Biology +22

Drugging an undruggable pocket on KRAS

Dirk Kessler, Michael Gmachl, Andreas Mantoulidis et al. · Proceedings of the National Academy of Sciences · 2019 · 415 citations · Full text

Interaction with WDR5 Promotes Target Gene Recognition and Tumorigenesis by MYC

Lance R. Thomas, Qingguo Wang, Brian C. Grieb et al. · Molecular Cell · 2015 · 308 citations · Full text

Cell Regulation, Medicine, Cancer Genomics +8

Structural Basis for the Substrate Specificity of Tobacco Etch Virus Protease

Jason Phan, Alexander Zdanov, A.G. Evdokimov et al. · Journal of Biological Chemistry · 2002 · 255 citations · Full text

Approach for targeting Ras with small molecules that activate SOS-mediated nucleotide exchange

Michael C. Burns, Qi Sun, R. Nathan Daniels et al. · Proceedings of the National Academy of Sciences · 2014 · 187 citations · Full text