Lance R. Thomas

Interaction with WDR5 Promotes Target Gene Recognition and Tumorigenesis by MYC

Lance R. Thomas, Qingguo Wang, Brian C. Grieb et al. · Molecular Cell · 2015 · 317 citations · Full text

Medicine, Cancer Biology, Molecular Biology +11

Interaction of the oncoprotein transcription factor MYC with its chromatin cofactor WDR5 is essential for tumor maintenance

Lance R. Thomas, Clare M. Adams, Jing Wang et al. · Proceedings of the National Academy of Sciences · 2019 · 124 citations · Full text

Medicine, Cancer Biology, Oncology +14

Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity

Erin R. Aho, Jing Wang, Rocco D. Gogliotti et al. · Cell Reports · 2019 · 123 citations · Full text

Life Sciences, Molecular Biology, Oncology +10

Selective Inactivation of a Fas-associated Death Domain Protein (FADD)-dependent Apoptosis and Autophagy Pathway in Immortal Epithelial Cells

Jacqueline Thorburn, Franklin Moore, Anuradha Rao et al. · Molecular Biology of the Cell · 2005 · 106 citations · Full text

Life Sciences, Cell Biology, Oncology +17

MYC regulates ribosome biogenesis and mitochondrial gene expression programs through its interaction with host cell factor–1

Tessa M. Popay, Jing Wang, Clare M. Adams et al. · eLife · 2021 · 103 citations · Full text

Medicine, Cancer Biology, Oncology +15