Michael Gmachl

SNAREpins: Minimal Machinery for Membrane Fusion

Thomas Weber, Boris V. Zemelman, James A. McNew et al. · Cell · 1998 · 2.5K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Drugging an undruggable pocket on KRAS

Dirk Kessler, Michael Gmachl, Andreas Mantoulidis et al. · Proceedings of the National Academy of Sciences · 2019 · 434 citations · Full text

Medicine, Molecular Biology, Oncology +15

KRAS Secondary Mutations That Confer Acquired Resistance to KRAS G12C Inhibitors, Sotorasib and Adagrasib, and Overcoming Strategies: Insights From In Vitro Experiments

T. Koga, Kenichi Suda, Toshio Fujino et al. · Journal of Thoracic Oncology · 2021 · 251 citations · Full text

Medicine, Genetics, Molecular Genetics +15

Bee venom hyaluronidase is homologous to a membrane protein of mammalian sperm.

Michael Gmachl, G. Kreil · Proceedings of the National Academy of Sciences · 1993 · 206 citations

Life Sciences, Entomology, Molecular Biology +14

The RING-H2 finger protein APC11 and the E2 enzyme UBC4 are sufficient to ubiquitinate substrates of the anaphase-promoting complex

Michael Gmachl, Christian Gieffers, Alexandre V. Podtelejnikov et al. · Proceedings of the National Academy of Sciences · 2000 · 185 citations

Life Sciences, Biochemistry, Molecular Biology +13