Concepedia

Jason P. Burke

JP

14

Publications

1.4K

Citations

13

H-Index

2004

Active since

Affiliations

The University of Texas MD Anderson Cancer Center(Current)

Vanderbilt University

Tesaro (United States)

University of Manchester

Jason P. Burke is an author at The University of Texas MD Anderson Cancer Center specializing in pharmacology, drug discovery, and medicine.

ORCID

Top concepts

Publications per year

2004–2021

14

Publications

14

Discovery of Small Molecules that Bind to K‐Ras and Inhibit Sos‐Mediated Activation

Qi Sun, Jason P. Burke, Jason Phan et al. · Angewandte Chemie International Edition · 2012 · 495 citations

, , +22

Discovery of Potent Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods and Structure-Based Design

Anders Friberg, Dominico Vigil, Bin Zhao et al. · Journal of Medicinal Chemistry · 2012 · 302 citations · Full text

, , +16

Allosteric SHP2 Inhibitor, IACS-13909, Overcomes EGFR-Dependent and EGFR-Independent Resistance Mechanisms toward Osimertinib

Yuting Sun, Brooke A. Meyers, Barbara Czakó et al. · Cancer Research · 2020 · 101 citations · Full text

Discovery of Tricyclic Indoles That Potently Inhibit Mcl-1 Using Fragment-Based Methods and Structure-Based Design

Jason P. Burke, Zhiguo Bian, Subrata Shaw et al. · Journal of Medicinal Chemistry · 2015 · 95 citations · Full text

, , +18

Discovery of IPN60090, a Clinical Stage Selective Glutaminase-1 (GLS-1) Inhibitor with Excellent Pharmacokinetic and Physicochemical Properties

Michael Soth, Kang Le, Maria Emilia Di Francesco et al. · Journal of Medicinal Chemistry · 2020 · 88 citations · Full text

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