Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas

Chan Chung, Stefan R. Sweha, Drew Pratt, +21

Cancer Cell

Neuro-oncologySomatic VariantTumor HeterogeneityEpigenomic ReprogramingCancer Genomics +8

Discovery of 2-Indole-acylsulfonamide Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods

Nicholas F. Pelz, Zhiguo Bian, Bin Zhao, +13

Journal of Medicinal Chemistry

Drug TargetMolecular BiologyTumor BiologyMyeloid NeoplasiaHematological Malignancy +14

CeO2-modified CaO/Ca12Al14O33 bi-functional material for CO2 capture and H2 production in sorption-enhanced steam gasification of biomass

Xianyao Yan, Yingjie Li, Xiaotong Ma, +3

Energy

Chemical EngineeringBiomass ConversionEngineeringBioenergyGas Conversion +11

Enantioselective Total Synthesis of (−)-Citrinadin A and Revision of Its Stereochemical Structure

Zhiguo Bian, Christopher C. Marvin, Stephen F. Martin

Journal of the American Chemical Society

Available MaterialsBioorganic ChemistryEngineeringBiochemistryNatural Sciences +12

Discovery of Tricyclic Indoles That Potently Inhibit Mcl-1 Using Fragment-Based Methods and Structure-Based Design

Jason P. Burke, Zhiguo Bian, Subrata Shaw, +11

Journal of Medicinal Chemistry

Combinatorial ChemistryDrug TargetMolecular BiologyHeterocycle ChemistryChemical Biology +16

Thermochemical energy storage performances of Ca-based natural and waste materials under high pressure during CaO/CaCO3 cycles

Hao Sun, Yingjie Li, Zhiguo Bian, +3

Energy Conversion and Management

Materials ScienceChemical EngineeringEngineeringEnergy EfficiencyCao/caco3 Cycles +6

Enantioselective Total Syntheses of Citrinadins A and B. Stereochemical Revision of Their Assigned Structures

Zhiguo Bian, Christopher C. Marvin, Martin Pettersson, +1

Journal of the American Chemical Society

Discovery of Potent Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors That Demonstrate in Vivo Activity in Mouse Xenograft Models of Human Cancer

Taekyu Lee, Plamen P. Christov, Subrata Shaw, +24

Journal of Medicinal Chemistry

Hematological MalignancyTumor BiologyMouse Xenograft ModelsVivo ActivityCompound 42 +13

Novel Modes of Inhibition of Wild-Type Isocitrate Dehydrogenase 1 (IDH1): Direct Covalent Modification of His315

Clarissa G. Jakob, Anup K. Upadhyay, Pamela L. Donner, +15

Journal of Medicinal Chemistry

Molecular BiologyChemical BiologyRedox BiologyActive Site H315Novel Modes +15

Simultaneous CO2 capture and thermochemical heat storage by modified carbide slag in coupled calcium looping and CaO/Ca(OH)2 cycles

Chunxiao Zhang, Yingjie Li, Zhiguo Bian, +2

Chinese Journal of Chemical Engineering

Materials ScienceChemical EngineeringCarbonizationEngineeringModified Carbide Slag +3