Chan Chung

Immunohistochemical analysis of H3K27me3 demonstrates global reduction in group-A childhood posterior fossa ependymoma and is a powerful predictor of outcome

Pooja Panwalkar, Jonathan R. Clark, Vijay Ramaswamy et al. · Acta Neuropathologica · 2017 · 248 citations

Medicine, Pathology, Pediatrics +16

Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas

Chan Chung, Stefan R. Sweha, Drew Pratt et al. · Cancer Cell · 2020 · 221 citations · Full text

Medicine, Genetics, Oncology +12

Lowered H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas

Jill Bayliss, Piali Mukherjee, Chao Lü et al. · Science Translational Medicine · 2016 · 192 citations · Full text

Medicine, Oncology, Pediatrics +16

Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways

Sriram Venneti, Abed Rahman Kawakibi, Sunjong Ji et al. · Cancer Discovery · 2023 · 154 citations · Full text

Medicine, Cancer Biology, Oncology +14

Impaired proteolysis underlies autophagic dysfunction in Niemann–Pick type C disease

Matthew J. Elrick, Ting Yu, Chan Chung et al. · Human Molecular Genetics · 2012 · 149 citations

Life Sciences, Cell Biology, Neurology +17