Chan Chung

Immunohistochemical analysis of H3K27me3 demonstrates global reduction in group-A childhood posterior fossa ependymoma and is a powerful predictor of outcome

Pooja Panwalkar, Jonathan R. Clark, Vijay Ramaswamy et al. · Acta Neuropathologica · 2017 · 229 citations · Full text

Neuro-oncology, Global Reduction, Powerful Predictor +6

Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas

Chan Chung, Stefan R. Sweha, Drew Pratt et al. · Cancer Cell · 2020 · 204 citations · Full text

Neuro-oncology, Somatic Variant, Tumor Heterogeneity +10

Lowered H3K27me3 and DNA hypomethylation define poorly prognostic pediatric posterior fossa ependymomas

Jill Bayliss, Piali Mukherjee, Chao Lü et al. · Science Translational Medicine · 2016 · 187 citations · Full text

Impaired proteolysis underlies autophagic dysfunction in Niemann–Pick type C disease

Matthew J. Elrick, Ting Yu, Chan Chung et al. · Human Molecular Genetics · 2012 · 146 citations · Full text

Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways

Sriram Venneti, Abed Rahman Kawakibi, Sunjong Ji et al. · Cancer Discovery · 2023 · 130 citations · Full text