Tremelimumab in combination with ablation in patients with advanced hepatocellular carcinoma

Austin G. Duffy, Susanna V. Ulahannan, Oxana Makorova-Rusher, +19

Journal of Hepatology

HepatologyMedicinePathologyLiver CancerCancer Treatment +4

Purine metabolism regulates DNA repair and therapy resistance in glioblastoma

Weihua Zhou, Yangyang Yao, Andrew J. Scott, +25

Nature Communications

Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas

Chan Chung, Stefan R. Sweha, Drew Pratt, +21

Cancer Cell

Neuro-oncologySomatic VariantTumor HeterogeneityEpigenomic ReprogramingCancer Genomics +8

The effect of anti-CTLA4 treatment on peripheral and intra-tumoral T cells in patients with hepatocellular carcinoma

David Agdashian, Mei ElGindi, Changqing Xie, +13

Cancer Immunology Immunotherapy

Cancer ImmunosurveillanceHepatologyIntra-tumoral T CellsHepatocellular CarcinomaAnti-ctla4 Treatment +7

Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways

Sriram Venneti, Abed Rahman Kawakibi, Sunjong Ji, +81

Cancer Discovery

Impact of the methylation classifier and ancillary methods on CNS tumor diagnostics

Zhichao Wu, Zied Abdullaev, Drew Pratt, +27

Neuro-Oncology

ATRX loss in glioma results in dysregulation of cell-cycle phase transition and ATM inhibitor radio-sensitization

Tingting Qin, Brendan Mullan, Ramya Ravindran, +24

Cell Reports

Atrx-deficient Gbm CellsCell CycleHigh-grade GliomasGliomaTumor Biology +14

Combined Small Cell Carcinoma of the Lung: Is It a Single Entity?

Xiaoliang Zhao, Justine N. McCutcheon, Bhaskar Kallakury, +6

Journal of Thoracic Oncology

MedicineMultiple Pulmonary NoduleSingle EntitySmall Cell CarcinomaPathology +6

A Novel Behavioral Test Battery to Assess Global Drug Effects Using the Zebrafish

David J. Echevarria, Catherine M. Hammack‐Aviran, Drew Pratt, +1

International Journal of Comparative Psychology

Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas

Pooja Panwalkar, Benita Tamrazi, Derek Dang, +42

Science Translational Medicine