Dominico Vigil

Discovery of Potent Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods and Structure-Based Design

Anders Friberg, Dominico Vigil, Bin Zhao et al. · Journal of Medicinal Chemistry · 2012 · 302 citations · Full text

Lead Compounds, Drug Target, Large Fragment Library +16

Identification and Characterization of Von Hippel-Lindau-Recruiting Proteolysis Targeting Chimeras (PROTACs) of TANK-Binding Kinase 1

Andrew P. Crew, Kanak Raina, Hanqing Dong et al. · Journal of Medicinal Chemistry · 2017 · 246 citations · Full text

ROCK1 and ROCK2 Are Required for Non-Small Cell Lung Cancer Anchorage-Independent Growth and Invasion

Dominico Vigil, Tai Young Kim, Ana Plachco et al. · Cancer Research · 2012 · 136 citations · Full text

Discovery of Tricyclic Indoles That Potently Inhibit Mcl-1 Using Fragment-Based Methods and Structure-Based Design

Jason P. Burke, Zhiguo Bian, Subrata Shaw et al. · Journal of Medicinal Chemistry · 2015 · 95 citations · Full text

Combinatorial Chemistry, Drug Target, Molecular Biology +18

Functional Dynamics of the Hydrophobic Cleft in the N-Domain of Calmodulin

Dominico Vigil, Stephen C. Gallagher, Jill Trewhella et al. · Biophysical Journal · 2001 · 84 citations · Full text

Hydrophobic Cleft, Protein Chemistry, Proteinlipid Interaction +10