Hanqing Dong

Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4

Jing Lü, Yimin Qian, Martha Altieri et al. · Chemistry & Biology · 2015 · 1.1K citations · Full text

Life Sciences, Genetics, Molecular Biology +6

PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer

Kanak Raina, Jing Lü, Yimin Qian et al. · Proceedings of the National Academy of Sciences · 2016 · 827 citations · Full text

Medicine, Molecular Biology, Oncology +17

The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case Study

George M. Burslem, Blake E. Smith, Ashton C. Lai et al. · Cell chemical biology · 2017 · 673 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Rhodium-Catalyzed Asymmetric Arylation

Ping Tian, Hanqing Dong, Guo‐Qiang Lin · ACS Catalysis · 2011 · 428 citations

Natural Sciences, Chemistry, Catalysis +9

Androgen receptor degradation by the proteolysis-targeting chimera ARCC-4 outperforms enzalutamide in cellular models of prostate cancer drug resistance

Jemilat Salami, Shanique Alabi, Ryan R. Willard et al. · Communications Biology · 2018 · 346 citations · Full text

Medicine, Oncology, Pharmacology +16