Maryann C. Zounes

Uniformly modified 2'-deoxy-2'-fluoro-phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets

Andrew M. Kawasaki, Martin D. Casper, Susan M. Freier et al. · Journal of Medicinal Chemistry · 1993 · 436 citations

Life Sciences, Molecular Biology, Bioorthogonal Chemistry +16

Effects of phosphorothioate capping on antivense oligonucleotide stability, hybridization and antiviral efficacy versus herpes simplex virus infection

Glenn D. Hoke, Kenneth Draper, Susan M. Freier et al. · Nucleic Acids Research · 1991 · 248 citations · Full text

Medicine, Infectious Diseases, Pharmacology +13

Oligodeoxynucleotides containing 2'-O-modified adenosine: Synthesis and effects on stability of DNA:RNA duplexes

Elena A. Lesnik, Charles J. Guinosso, Andrew M. Kawasaki et al. · Biochemistry · 1993 · 202 citations

Pharmacy, Biochemistry, Molecular Biology +17

Inhibition of HIV-LTR gene expression by oligonucleotides targeted to the TAR element

Timothy A. Vickers, Brenda F. Baker, P. Dan Cook et al. · Nucleic Acids Research · 1991 · 133 citations · Full text

Life Sciences, Biology, Molecular Biology +15

Pseudo—Half-Knot Formation with RNA

David J. Ecker, Timothy A. Vickers, T. W. Bruice et al. · Science · 1992 · 94 citations

Life Sciences, Biology, Molecular Biology +15