Concepedia

Author

Jan Balzarini

KU Leuven

Also Known As

Jan Balzarini

10

Publications

645

Citations

8

H-Index

19

Concepts

All Affiliations

KU LeuvenRega Institute for Medical ResearchCardiff UniversityUniversity of WalesErasmus University Rotterdam
JB

About

Jan Balzarini is an author at KU Leuven specializing in medicine, drug discovery, and pharmacology.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

5

5

222

2

Natural Sciences

3

3

97

3

Chemistry

2

2

85

4

Biochemistry

1

1

60

5

Biomolecular Engineering

1

1

17

Jan Balzarini

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8

Publications

634

Citations

8

H-Index

YearCitations

9-(2-phosphonylmethoxyethyl)adenine (PMEA) effectively inhibits retrovirus replication in vitro and simian immunodeficiency virus infection in rhesus monkeys

Jan Balzarini, Lieve Naesens, J. F. A. M. Slachmuylders,

AIDS

1991

214

A new class of HIV-1 specific 6-substituted acyclouridine derivatives: synthesis and anti-HIV-1 activity of 5- or 6-substituted analogs of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT)

Hiromichi Tanaka, Masanori Baba, Hiroyuki Hayakawa,

Journal of Medicinal Chemistry

1991

138

Synthesis and evaluation of novel amidate prodrugs of PMEA and PMPA

Carlo Ballatore, Christopher McGuigan, Erik De Clercq,

Bioorganic & Medicinal Chemistry Letters

2001

65

Conversion of 2′,3′‐dideoxyadenosine (ddA) and 2′,3′‐didehydro‐2′,3′‐dideoxyadenosine (d4A) to their corresponding aryloxyphosphoramidate derivatives markedly potentiates their activity against human immunodeficiency virus and hepatitis B virus

Jan Balzarini, J. Kruining, Orson Wedgwood,

FEBS Letters

1997

60

Anti-HIV and Anti-HBV Activity and Resistance Profile of 2′,3′-Dideoxy-3′-Thiacytidine (3TC) and Its Arylphosphoramidate Derivative CF 1109

Jan Balzarini, Orson Wedgwood, J. Kruining,

Biochemical and Biophysical Research Communications

1996

60

Cyclosaligenyl-2′,3′-didehydro-2′,3′-dideoxythymidine Monophosphate: Efficient Intracellular Delivery of d4TMP

Jan Balzarini, Stefano Aquaro, Tina Knispel,

Molecular Pharmacology

2000

60

Synthesis of 3-Nitrosoimidazo[1,2-a]pyridine Derivatives as Potential Antiretroviral Agents

Aziz Chaouni-Benabdallah, Christophe Galtier, H. Allouchi,

Archiv der Pharmazie

2001

20

Mutations at Amino Acid Positions 63, 189, and 396 of Human Immunodeficiency Virus Type 1 Reverse Transcriptase (RT) Partially Restore the DNA Polymerase Activity of a TRP229TYR Mutant RT

Heidi Pelemans, Robert Esnouf, Kyung‐Lyum Min,

Virology

2001

17

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