Hiromichi Tanaka

A novel lead for specific anti-HIV-1 agents: 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine

Tadashi Miyasaka, Hiromichi Tanaka, Masanori Baba et al. · Journal of Medicinal Chemistry · 1989 · 382 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Complexes of HIV-1 Reverse Transcriptase with Inhibitors of the HEPT Series Reveal Conformational Changes Relevant to the Design of Potent Non-Nucleoside Inhibitors

Andrew L. Hopkins, Jingshan Ren, Robert Esnouf et al. · Journal of Medicinal Chemistry · 1996 · 343 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +16

Synthesis and antiviral activity of deoxy analogs of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT) as potent and selective anti-HIV-1 agents

Hiromichi Tanaka, Hideaki Takashima, Masaru Ubasawa et al. · Journal of Medicinal Chemistry · 1992 · 166 citations

Pharmacy, Medicinal Chemistry, Pharmacology +11

Synthesis and Antiviral Activity of 6-Benzyl Analogs of 1-[(2-Hydroxyethoxy)methyl]-5-(phenylthio)thymine (HEPT) as Potent and Selective Anti-HIV-1 Agents

Hiromichi Tanaka, Hideaki Takashima, Masaru Ubasawa et al. · Journal of Medicinal Chemistry · 1995 · 156 citations

Pharmacy, Medicinal Chemistry, Pharmacology +9

Structure-activity relationships of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine analogs: effect of substitutions at the C-6 phenyl ring and at the C-5 position on anti-HIV-1 activity

Hiromichi Tanaka, Hideaki Takashima, Masaru Ubasawa et al. · Journal of Medicinal Chemistry · 1992 · 139 citations

Medicine, Chemistry, Pharmacology +15