Tadashi Miyasaka

A novel lead for specific anti-HIV-1 agents: 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine

Tadashi Miyasaka, Hiromichi Tanaka, Masanori Baba et al. · Journal of Medicinal Chemistry · 1989 · 378 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Novel Lead +15

Complexes of HIV-1 Reverse Transcriptase with Inhibitors of the HEPT Series Reveal Conformational Changes Relevant to the Design of Potent Non-Nucleoside Inhibitors

Andrew L. Hopkins, Jingshan Ren, Robert Esnouf et al. · Journal of Medicinal Chemistry · 1996 · 339 citations · Full text

Biochemistry, Protein Folding, Medicine +15

Synthesis and Antitumor Activity of 20(S)-Camptothecin Derivatives: Carbamate-Linked, Water-Soluble Derivatives of 7-Ethyl-10-hydroxycamptothecin.

Seigo Sawada, Satoru Okajima, Ritsuo Aiyama et al. · Chemical and Pharmaceutical Bulletin · 1991 · 232 citations · Full text

Antitumor Activity, Novel 36, Organic Chemistry +16

Synthesis and antiviral activity of deoxy analogs of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT) as potent and selective anti-HIV-1 agents

Hiromichi Tanaka, Hideaki Takashima, Masaru Ubasawa et al. · Journal of Medicinal Chemistry · 1992 · 166 citations

Synthesis and Antiviral Activity of 6-Benzyl Analogs of 1-[(2-Hydroxyethoxy)methyl]-5-(phenylthio)thymine (HEPT) as Potent and Selective Anti-HIV-1 Agents

Hiromichi Tanaka, Hideaki Takashima, Masaru Ubasawa et al. · Journal of Medicinal Chemistry · 1995 · 155 citations

Altmetric Attention Score, Organic Chemistry, Antiviral Drug +16