J. Kruining

Inhibitory effect of 9-(2-phosphonylmethoxyethyl)adenine (PMEA) on human and duck hepatitis B virus infection

R. A. Heijtink, G.A. de Wilde, J. Kruining et al. · Antiviral Research · 1993 · 119 citations

Viral Hepatitis, Medicine, Antiviral Therapy +8

Inhibitory effects of acyclic nucleoside phosphonates on human hepatitis B virus and duck hepatitis B virus infections in tissue culture

R. A. Heijtink, J. Kruining, G.A. de Wilde et al. · Antimicrobial Agents and Chemotherapy · 1994 · 93 citations · Full text

Adenine-related Compounds, Inhibitory Effects, Biochemistry +15

Conversion of 2′,3′‐dideoxyadenosine (ddA) and 2′,3′‐didehydro‐2′,3′‐dideoxyadenosine (d4A) to their corresponding aryloxyphosphoramidate derivatives markedly potentiates their activity against human immunodeficiency virus and hepatitis B virus

Jan Balzarini, J. Kruining, Orson Wedgwood et al. · FEBS Letters · 1997 · 60 citations · Full text

Immunology, Cell Culture, Antiviral Drug +21

Anti-HIV and Anti-HBV Activity and Resistance Profile of 2′,3′-Dideoxy-3′-Thiacytidine (3TC) and Its Arylphosphoramidate Derivative CF 1109

Jan Balzarini, Orson Wedgwood, J. Kruining et al. · Biochemical and Biophysical Research Communications · 1996 · 60 citations · Full text

Medicinal Chemistry, Anti-hbv Activity, Medicine +10

Serum HBeAg quantitation during antiviral therapy for chronic hepatitis B

Rudolf A. Heijtink, J. Kruining, Pieter Honkoop et al. · Journal of Medical Virology · 1997 · 40 citations

Hepatitis Be Antigen, Hepatology, Viral Hepatitis +11