Masao Iwata

Splicing factor SF3b as a target of the antitumor natural product pladienolide

Yoshihiko Kotake, Koji Sagane, Takashi Owa et al. · Nature Chemical Biology · 2007 · 649 citations · Full text

Oncogenic Agent, Medicine, Factor Sf3b +5

Antitumor Activity of Lenvatinib (E7080): An Angiogenesis Inhibitor That Targets Multiple Receptor Tyrosine Kinases in Preclinical Human Thyroid Cancer Models

Osamu Tohyama, Junji Matsui, Kotaro Kodama et al. · Journal of Thyroid Research · 2014 · 468 citations · Full text

Antitumor Activity, Angiogenesis Inhibitor, Pathology +17

Antitumor activities of the targeted multi-tyrosine kinase inhibitor lenvatinib (E7080) against RET gene fusion-driven tumor models

Kiyoshi Okamoto, Kotaro Kodama, Kazuma Takase et al. · Cancer Letters · 2013 · 282 citations · Full text

Cancer Biology, Tumor Biology, Oncology +17

Pladienolides, New Substances from Culture of Streptomyces platensis Mer-11107 III. In Vitro and In Vivo Antitumor Activities

Yoshiharu Mizui, Takashi Sakai, Masao Iwata et al. · The Journal of Antibiotics · 2004 · 185 citations · Full text

Biological validation that SF3b is a target of the antitumor macrolide pladienolide

Akira Yokoi, Yoshihiko Kotake, Kentaro Takahashi et al. · FEBS Journal · 2011 · 178 citations · Full text

Widr Cells, Tumor Biology, Oncology +14