Yoshihiko Kotake

Splicing factor SF3b as a target of the antitumor natural product pladienolide

Yoshihiko Kotake, Koji Sagane, Takashi Owa et al. · Nature Chemical Biology · 2007 · 649 citations · Full text

Oncogenic Agent, Medicine, Factor Sf3b +5

Selective degradation of splicing factor CAPERα by anticancer sulfonamides

Taisuke Uehara, Yukinori Minoshima, Koji Sagane et al. · Nature Chemical Biology · 2017 · 366 citations

Medicinal Chemistry, Medicine, Natural Sciences +6

Novel sulfonamides as potential, systemically active antitumor agents

Hiroshi Yoshino, Norihiro Ueda, Jun Niijima et al. · Journal of Medicinal Chemistry · 1992 · 233 citations

Chemoprevention Strategy, Altmetric Attention Score, Pharmacotherapy +20

Biological validation that SF3b is a target of the antitumor macrolide pladienolide

Akira Yokoi, Yoshihiko Kotake, Kentaro Takahashi et al. · FEBS Journal · 2011 · 178 citations · Full text

Widr Cells, Tumor Biology, Oncology +14

2-Alkynyl-8-aryl-9-methyladenines as Novel Adenosine Receptor Antagonists:  Their Synthesis and Structure−Activity Relationships toward Hepatic Glucose Production Induced via Agonism of the A_2BReceptor

Hitoshi Harada, Osamu Asano, Yorihisa Hoshino et al. · Journal of Medicinal Chemistry · 2000 · 111 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +13