Selective degradation of splicing factor CAPERα by anticancer sulfonamides

Taisuke Uehara, Yukinori Minoshima, Koji Sagane, +13

Nature Chemical Biology

Medicinal ChemistryMedicineNatural SciencesAnti-cancer AgentChemical Biology +4

Targeting an RNA-Binding Protein Network in Acute Myeloid Leukemia

Eric Wang, Sydney X. Lu, Alessandro Pastore, +18

Cancer Cell

Rna-binding Protein NetworkRna Binding ProteinsRna Structure PredictionSystems BiologyCell Biology +1

Eribulin mesylate reduces tumor microenvironment abnormality by vascular remodeling in preclinical human breast cancer models

Yasuhiro Funahashi, Kiyoshi Okamoto, Yusuke Adachi, +15

Cancer Science

Breast OncologyBiological MicroenvironmentsPathologyMicroenvironment AbnormalityCancer Biology +17

Highly Accurate Chemical Formula Prediction Tool Utilizing High-Resolution Mass Spectra, MS/MS Fragmentation, Heuristic Rules, and Isotope Pattern Matching

Tomáš Pluskal, Taisuke Uehara, Mitsuhiro Yanagida

Analytical Chemistry

EngineeringChemical AnalysisSource Code RepositoryMetabolomic ProfilingComputational Chemistry +23

Final results of a phase 2, open‐label study of indisulam, idarubicin, and cytarabine in patients with relapsed or refractory acute myeloid leukemia and high‐risk myelodysplastic syndrome

Rita Assi, Hagop M. Kantarjian, Tapan M. Kadia, +9

Cancer

Schulzeines A−C, New α-Glucosidase Inhibitors from the Marine Sponge <i>Penares schulzei</i>¹

Kentaro Takada, Taisuke Uehara, Yoichi Nakao, +3

Journal of the American Chemical Society

Polar Anionic Metabolome Analysis by Nano-LC/MS with a Metal Chelating Agent

Khin Than Myint, Taisuke Uehara, Ken Aoshima, +1

Analytical Chemistry

Callyspongynic Acid, a Polyacetylenic Acid Which Inhibits α-Glucosidase, from the Marine Sponge <i>Callyspongia </i><i>t</i><i>runcata</i>

Yoichi Nakao, Taisuke Uehara, Shigeki Matunaga, +2

Journal of Natural Products

Quantitative Phosphorus Metabolomics Using Nanoflow Liquid Chromatography-Tandem Mass Spectrometry and Culture-Derived Comprehensive Global Internal Standards

Taisuke Uehara, Akira Yokoi, Ken Aoshima, +4

Analytical Chemistry

Biological Mass SpectrometryMetabolomic ProfilingQuantitative ReproducibilityBioanalysisAnalytical Chemistry +15

Practical metabolomics in drug discovery

Keith Wilcoxen, Taisuke Uehara, Khin Than Myint, +2

Expert Opinion on Drug Discovery