Kiyoshi Okamoto

Antitumor Activity of Lenvatinib (E7080): An Angiogenesis Inhibitor That Targets Multiple Receptor Tyrosine Kinases in Preclinical Human Thyroid Cancer Models

Osamu Tohyama, Junji Matsui, Kotaro Kodama et al. · Journal of Thyroid Research · 2014 · 480 citations · Full text

Medicine, Oncology, Pharmacology +17

Antitumor activities of the targeted multi-tyrosine kinase inhibitor lenvatinib (E7080) against RET gene fusion-driven tumor models

Kiyoshi Okamoto, Kotaro Kodama, Kazuma Takase et al. · Cancer Letters · 2013 · 286 citations · Full text

Medicine, Oncology, Pharmacology +17

Distinct Binding Mode of Multikinase Inhibitor Lenvatinib Revealed by Biochemical Characterization

Kiyoshi Okamoto, Megumi Ikemori‐Kawada, A. Jestel et al. · ACS Medicinal Chemistry Letters · 2014 · 278 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Eribulin mesylate reduces tumor microenvironment abnormality by vascular remodeling in preclinical human breast cancer models

Yasuhiro Funahashi, Kiyoshi Okamoto, Yusuke Adachi et al. · Cancer Science · 2014 · 278 citations · Full text

Medicine, Oncology, Pharmacology +17

Pladienolides, New Substances from Culture of Streptomyces platensis Mer-11107 III. In Vitro and In Vivo Antitumor Activities

Yoshiharu Mizui, Takashi Sakai, Masao Iwata et al. · The Journal of Antibiotics · 2004 · 187 citations · Full text

Medicine, Microbiology, Pharmacology +4