H. Heaslet - Concepedia

Author

H. Heaslet

Pfizer (United States)

Also Known As

H. Heaslet, H.A. Heaslet, Holly A Heaslet, Holly A. Heaslet, Holly Heaslet

Publications

763

Citations

H-Index

Concepts

All Affiliations

Pfizer (United States)Scripps Research Institute University of Massachusetts Chan Medical School

About

H. Heaslet is an author at Pfizer (United States) specializing in structural biology, natural sciences, and molecular biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	4	4	128
2	Natural Sciences	4	4	128
3	Biochemistry	4	4	128
4	Molecular Biology	4	4	128
5	Structural Biology	4	4	128

H. Heaslet

Publications

652

Citations

H-Index

Page 1

	Year	Citations
A Copper(I)-Catalyzed 1,2,3-Triazole Azide−Alkyne Click Compound Is a Potent Inhibitor of a Multidrug-Resistant HIV-1 Protease Variant Michael J. Giffin, H. Heaslet, Ashraf Brik, Journal of Medicinal Chemistry	2008	241
Structural comparison of chromosomal and exogenous dihydrofolate reductase from <i>Staphylococcus aureus</i> in complex with the potent inhibitor trimethoprim H. Heaslet, Melissa S. Harris, Kelly Fahnoe, Proteins Structure Function and Bioinformatics	2009	132
Conformational flexibility in the flap domains of ligand-free HIV protease H. Heaslet, R.J. Rosenfeld, Mike Giffin, Acta Crystallographica Section D Biological Crystallography	2007	99
Characterization of the active site of S. aureus monofunctional glycosyltransferase (Mtg) by site-directed mutation and structural analysis of the protein complexed with moenomycin H. Heaslet, Bailin Shaw, Anil Mistry, Journal of Structural Biology Site-directed MutationBiochemistryNatural SciencesGlycobiologyMolecular Biology	2009	57
Crystal structure of an FIV/HIV chimeric protease complexed with the broad-based inhibitor, TL-3 H. Heaslet, Ying-Chuan Lin, Karen Tam, Retrovirology	2007	42
The 2.7 Å crystal structure of deoxygenated hemoglobin from the sea lamprey (Petromyzon marinus): structural basis for a lowered oxygen affinity and Bohr effect H. Heaslet, William E. Royer Structure Periodic Surface Structureså Crystal StructureBohr EffectBiochemistrySea Lamprey	1999	31
Structural Insights into the Mechanisms of Drug Resistance in HIV-1 Protease NL4-3 H. Heaslet, Victoria Kutilek, Garrett M. Morris, Journal of Molecular Biology BiochemistryProtein AssemblyNatural SciencesHuman RetrovirusAntiviral Drug Development	2005	21
Rational protein engineering in action: The first crystal structure of a phenylalanine tRNA synthetase from Staphylococcus haemolyticus A.G. Evdokimov, Marlene Mekel, Kim Hutchings, Journal of Structural Biology Phenylalanine Trna SynthetaseBiochemistryProtein FoldingNatural SciencesEnzyme Catalysis	2007	19
Crystalline Ligand Transitions in Lamprey Hemoglobin H. Heaslet, William E. Royer Journal of Biological Chemistry	2001	10

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