Michael J. Giffin

A Copper(I)-Catalyzed 1,2,3-Triazole Azide−Alkyne Click Compound Is a Potent Inhibitor of a Multidrug-Resistant HIV-1 Protease Variant

Michael J. Giffin, H. Heaslet, Ashraf Brik et al. · Journal of Medicinal Chemistry · 2008 · 244 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +17

AMG 757, a Half-Life Extended, DLL3-Targeted Bispecific T-Cell Engager, Shows High Potency and Sensitivity in Preclinical Models of Small-Cell Lung Cancer

Michael J. Giffin, Keegan S. Cooke, Edward K. Lobenhofer et al. · Clinical Cancer Research · 2020 · 238 citations · Full text

Medicine, Oncology, Pharmacology +15

Structure of NFAT1 bound as a dimer to the HIV-1 LTR κB element

Michael J. Giffin, James C. Stroud, D.L. Bates et al. · Nature Structural & Molecular Biology · 2003 · 105 citations

Life Sciences, Biochemistry, Molecular Biology +14

P3.12-03 Targeting DLL3 with AMG 757, a BiTE® Antibody Construct, and AMG 119, a CAR-T, for the Treatment of SCLC

Michael J. Giffin, Keegan S. Cooke, E. Lobenhofer et al. · Journal of Thoracic Oncology · 2018 · 35 citations · Full text

Pharmacy, Oncology, Antibody Engineering +8

Mutational Analysis of the Mu Transposase

Elena B. Krementsova, Michael J. Giffin, David Pincus et al. · Journal of Biological Chemistry · 1998 · 29 citations · Full text

Life Sciences, Genetics, Molecular Biology +14