Ashraf Brik

Small molecules targeting severe acute respiratory syndrome human coronavirus

Chung‐Yi Wu, Jia-Tsrong Jan, Shiou-Hwa Ma et al. · Proceedings of the National Academy of Sciences · 2004 · 537 citations · Full text

Medicine, Infectious Diseases, Pharmacology +14

1,2,3‐Triazole as a Peptide Surrogate in the Rapid Synthesis of HIV‐1 Protease Inhibitors

Ashraf Brik, Jerry Alexandratos, Ying‐Chuan Lin et al. · ChemBioChem · 2005 · 282 citations

Pharmacy, Medicinal Chemistry, Pharmacology +16

Highly Efficient and Chemoselective Peptide Ubiquitylation

K. S. Ajish Kumar, Mahmood Haj‐Yahya, Diana Olschewski et al. · Angewandte Chemie International Edition · 2009 · 253 citations · Full text

Life Sciences, Biochemistry, Chemical Biology +16

Structural basis for histone H2B deubiquitination by the SAGA DUB module

Michael T. Morgan, Mahmood Haj‐Yahya, Alison E. Ringel et al. · Science · 2016 · 250 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

A Copper(I)-Catalyzed 1,2,3-Triazole Azide−Alkyne Click Compound Is a Potent Inhibitor of a Multidrug-Resistant HIV-1 Protease Variant

Michael J. Giffin, H. Heaslet, Ashraf Brik et al. · Journal of Medicinal Chemistry · 2008 · 244 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +17