Ying‐Chuan Lin

Inhibitors of HIV‐1 Protease by Using In Situ Click Chemistry

Matthew Whiting, John Muldoon, Ying‐Chuan Lin et al. · Angewandte Chemie International Edition · 2006 · 506 citations

Poor Equals Potent, Click Chemistry, Antiviral Drug +17

1,2,3‐Triazole as a Peptide Surrogate in the Rapid Synthesis of HIV‐1 Protease Inhibitors

Ashraf Brik, Jerry Alexandratos, Ying‐Chuan Lin et al. · ChemBioChem · 2005 · 281 citations

Triazole Ring, Chemistry, Antiviral Drug +19

A Copper(I)-Catalyzed 1,2,3-Triazole Azide−Alkyne Click Compound Is a Potent Inhibitor of a Multidrug-Resistant HIV-1 Protease Variant

Michael J. Giffin, H. Heaslet, Ashraf Brik et al. · Journal of Medicinal Chemistry · 2008 · 241 citations · Full text

Rapid Discovery and Structure−Activity Profiling of Novel Inhibitors of Human Immunodeficiency Virus Type 1 Protease Enabled by the Copper(I)-Catalyzed Synthesis of 1,2,3-Triazoles and Their Further Functionalization

Matthew Whiting, Jonathan C. Tripp, Ying‐Chuan Lin et al. · Journal of Medicinal Chemistry · 2006 · 206 citations · Full text

Combinatorial Chemistry, Structure−activity Profiling, Click Chemistry +16

Rapid Diversity‐Oriented Synthesis in Microtiter Plates for In Situ Screening of HIV Protease Inhibitors

Ashraf Brik, John Muldoon, Ying‐Chuan Lin et al. · ChemBioChem · 2003 · 149 citations · Full text

Molecular Biology, Hiv Protease Inhibition, Chemistry +18