Inhibitors of HIV‐1 Protease by Using In Situ Click Chemistry

Abstract

Twice poor equals potent: HIV-1 Protease assembles its own potent inhibitor through formation of the triazole linkage from azide- and alkyne-containing fragments that are themselves poor binders. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2006/z502161_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.