Keegan S. Cooke

The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity

Jude Canon, Karen Rex, Anne Y. Saiki et al. · Nature · 2019 · 2.3K citations

Medicine, Oncology, Pharmacology +14

Antihepcidin antibody treatment modulates iron metabolism and is effective in a mouse model of inflammation-induced anemia

Barbra J. Sasu, Keegan S. Cooke, Tara Arvedson et al. · Blood · 2010 · 249 citations

Medicine, Hematology, Immunology +15

AMG 757, a Half-Life Extended, DLL3-Targeted Bispecific T-Cell Engager, Shows High Potency and Sensitivity in Preclinical Models of Small-Cell Lung Cancer

Michael J. Giffin, Keegan S. Cooke, Edward K. Lobenhofer et al. · Clinical Cancer Research · 2020 · 238 citations · Full text

Medicine, Oncology, Pharmacology +15

Molecular Mechanism of Hepcidin-Mediated Ferroportin Internalization Requires Ferroportin Lysines, Not Tyrosines or JAK-STAT

Sandra L. Ross, Lynn Tran, Aaron Winters et al. · Cell Metabolism · 2012 · 141 citations · Full text

Medicine, Biochemistry, Cell Biology +9

A fully human anti-hepcidin antibody modulates iron metabolism in both mice and nonhuman primates

Keegan S. Cooke, Beth Hinkle, Hossein Salimi-Moosavi et al. · Blood · 2013 · 112 citations · Full text

Medicine, Hematology, Immunology +13