β-Secretase Cleavage of Alzheimer's Amyloid Precursor Protein by the Transmembrane Aspartic Protease BACE

Robert Vassar, Brian D. Bennett, Safura Babu‐Khan, +21

Science

The antiproliferative activity of c-myb and c-myc antisense oligonucleotides in smooth muscle cells is caused by a nonantisense mechanism.

Teresa L. Burgess, Eric F. Fisher, Sandra L. Ross, +7

Proceedings of the National Academy of Sciences

Molecular BiologyCytoskeletonCellular PhysiologyAngiogenesisNonantisense Mechanism +18

Characterization of Alzheimer's β-Secretase Protein BACE

Mitsuru Haniu, Paul Denis, Yunjen Young, +11

Journal of Biological Chemistry

Molecular Mechanism of Hepcidin-Mediated Ferroportin Internalization Requires Ferroportin Lysines, Not Tyrosines or JAK-STAT

Sandra L. Ross, Lynn Tran, Aaron Winters, +14

Cell Metabolism

Bioorganic ChemistryBiochemistryNatural SciencesMolecular MechanismMolecular Biology +4

Preclinical Evaluation of AMG 900, a Novel Potent and Highly Selective Pan-Aurora Kinase Inhibitor with Activity in Taxane-Resistant Tumor Cell Lines

Marc Payton, Tammy L. Bush, Grace Chung, +18

Cancer Research

Cell DeathNovel PotentCancer BiologyGliomaTumor Biology +16

Bispecific T cell engager (BiTE®) antibody constructs can mediate bystander tumor cell killing

Sandra L. Ross, Marika Sherman, Patricia McElroy, +5

PLoS ONE

ImmunologyImmunoeditingImmunodominanceImmunologic MechanismAntigen Processing +18

Biosynthetic Processing of neu Differentiation Factor

Teresa L. Burgess, Sandra L. Ross, Yixin Qian, +2

Journal of Biological Chemistry

Discovery of a Potent, Selective, and Orally Bioavailable Pyridinyl-Pyrimidine Phthalazine Aurora Kinase Inhibitor

Victor J. Cee, Laurie B. Schenkel, Brian L. Hodous, +28

Journal of Medicinal Chemistry

Pharmaceutical ScienceChemoprevention StrategyKinase InhibitorsChemical BiologyTumor Biology +14

Identification of Antibody and Small Molecule Antagonists of Ferroportin-Hepcidin Interaction

Sandra L. Ross, Kaustav Biswas, James B. Rottman, +5

Frontiers in Pharmacology

Small Molecule AntagonistsIron MetabolismControl FluxesIron DeficiencyRedox Biology +18

High-Content Screening Analysis of the p38 Pathway: Profiling of Structurally Related p38 <i>α</i> Kinase Inhibitors Using Cell-Based Assays

Sandra L. Ross, Teresa C. Chen, Violeta Yu, +6

Assay and Drug Development Technologies