Concepedia

Paul Denis

PD

7

Publications

5.8K

Citations

7

H-Index

1997

Active since

Affiliations

Amgen (United States)(Current)

Brigham and Women's Hospital

Harvard University

University of California, Santa Barbara

Paul Denis is an author at Amgen (United States) specializing in medicine, neurodegenerative diseases, and molecular neuroscience.

Top concepts

MedicineCell BiologyNatural SciencesMolecular BiologyNeurodegenerationAlzheimer's DiseaseMolecular NeuroscienceNeurodegenerative DiseasesNeurologyProteomics

Publications per year

1997–2002

7

Publications

7

β-Secretase Cleavage of Alzheimer's Amyloid Precursor Protein by the Transmembrane Aspartic Protease BACE

Robert Vassar, Brian D. Bennett, Safura Babu‐Khan et al. · Science · 1999 · 3.8K citations · Full text

Mice deficient in BACE1, the Alzheimer's β-secretase, have normal phenotype and abolished β-amyloid generation

Yi Luo, Brad Bolon, Steve Kahn et al. · Nature Neuroscience · 2001 · 991 citations

Neurodegenerative Diseases, Molecular Neuroscience, Alzheimer's Disease +13

Functional interactions between the proline-rich and repeat regions of tau enhance microtubule binding and assembly.

Bruce L. Goode, Paul Denis, Dulal Panda et al. · Molecular Biology of the Cell · 1997 · 283 citations

Repeat Regions, Protein Function, Molecular Neuroscience +15

A Furin-like Convertase Mediates Propeptide Cleavage of BACE, the Alzheimer's β-Secretase

Brian D. Bennett, Paul Denis, Mitsuru Haniu et al. · Journal of Biological Chemistry · 2000 · 269 citations · Full text

Structural and Functional Differences between 3-Repeat and 4-Repeat Tau Isoforms

Bruce L. Goode, M. F. Chau, Paul Denis et al. · Journal of Biological Chemistry · 2000 · 231 citations · Full text

Neurodegenerative Diseases, 4-Repeat Tau Isoforms, Alzheimer's Disease +13

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