Sclerostin Antibody Treatment Increases Bone Formation, Bone Mass, and Bone Strength in a Rat Model of Postmenopausal Osteoporosis

Xiaodong Li, Michael S. Ominsky, Kelly Warmington, +17

Journal of Bone and Mineral Research

SclerostinImmunologyOrthopaedic SurgeryRat ModelOsteoporosis +15

Antihepcidin antibody treatment modulates iron metabolism and is effective in a mouse model of inflammation-induced anemia

Barbra J. Sasu, Keegan S. Cooke, Tara Arvedson, +8

Blood

Molecular Mechanism of Hepcidin-Mediated Ferroportin Internalization Requires Ferroportin Lysines, Not Tyrosines or JAK-STAT

Sandra L. Ross, Lynn Tran, Aaron Winters, +14

Cell Metabolism

Bioorganic ChemistryBiochemistryNatural SciencesMolecular MechanismMolecular Biology +4

Dickkopf-1 regulates bone formation in young growing rodents and upon traumatic injury

Xiaodong Li, Mario Grisanti, Wei Fan, +37

Journal of Bone and Mineral Research

A fully human anti-hepcidin antibody modulates iron metabolism in both mice and nonhuman primates

Keegan S. Cooke, Beth Hinkle, Hossein Salimi-Moosavi, +8

Blood

Rapid single B cell antibody discovery using nanopens and structured light

Aaron Winters, Karyn McFadden, John R. Bergen, +7

mAbs

Immunocytochemical TechniqueEngineeringImmunologyBiomedical EngineeringImmunotherapy +14

Methylene blue-induced neuronal protective mechanism against hypoxia-reoxygenation stress

M.-G. Ryou, Gourav Roy Choudhury, Weimin Li, +3

Neuroscience

Redox RegulatorNeurophysiologyHypoxia-reoxygenation StressMedicinePhysiology +7

Identification of Antibody and Small Molecule Antagonists of Ferroportin-Hepcidin Interaction

Sandra L. Ross, Kaustav Biswas, James B. Rottman, +5

Frontiers in Pharmacology

Small Molecule AntagonistsIron MetabolismControl FluxesIron DeficiencyRedox Biology +18

An antibody to IP-10 is a potent antagonist of cell migration<i>in vitro</i>and<i>in vivo</i>and does not affect disease in several animal models of inflammation

Fergus R. Byrne, Aaron Winters, David Brankow, +27

Autoimmunity

Inhibition of WISE Preserves Renal Allograft Function

Xueming Qian, Xiaodong Yuan, Steven Vonderfecht, +23

Journal of the American Society of Nephrology