F. Christopher Zusi

BMS-345541 Is a Highly Selective Inhibitor of IκB Kinase That Binds at an Allosteric Site of the Enzyme and Blocks NF-κB-dependent Transcription in Mice

James R. Burke, Mark A. Pattoli, Kurt R. Gregor et al. · Journal of Biological Chemistry · 2003 · 532 citations · Full text

A highly selective inhibitor of IκB kinase, BMS‐345541, blocks both joint inflammation and destruction in collagen‐induced arthritis in mice

Kim W. McIntyre, David J. Shuster, Kathleen M. Gillooly et al. · Arthritis & Rheumatism · 2003 · 217 citations

Rational design of RAR‐selective ligands revealed by RARβ crystal stucture

Pierre Germain, Sabrina Kammerer, Efrén Pérez‐Santín et al. · EMBO Reports · 2004 · 86 citations · Full text

Crystal Structure, Engineering, Rational Design +4

Synthesis and biological evaluation of 4-amino derivatives of benzimidazoquinoxaline, benzimidazoquinoline, and benzopyrazoloquinazoline as potent IKK inhibitors

Françis Beaulieu, Carl Ouellet, Edward H. Ruediger et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 53 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +12

An inhibitor of I?B kinase, BMS-345541, blocks endothelial cell adhesion molecule expression and reduces the severity of dextran sulfate sodium-induced colitis in mice

John F. MacMaster, Donna M. Dambach, Yuping Qiu et al. · Inflammation Research · 2003 · 53 citations

Inflammation, Anti-inflammatory, Autoimmune Disease +11