Edward H. Ruediger

Hepatitis C Virus NS5A Replication Complex Inhibitors: The Discovery of Daclatasvir

Makonen Belema, Van N. Nguyen, Carol Bachand et al. · Journal of Medicinal Chemistry · 2014 · 87 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

The effects of NS5A inhibitors on NS5A phosphorylation, polyprotein processing and localization

Dike Qiu, Julie A. Lemm, Donald R. O’Boyle et al. · Journal of General Virology · 2011 · 60 citations

Life Sciences, Molecular Biology, Pharmacology +17

Synthesis and biological evaluation of 4-amino derivatives of benzimidazoquinoxaline, benzimidazoquinoline, and benzopyrazoloquinazoline as potent IKK inhibitors

Françis Beaulieu, Carl Ouellet, Edward H. Ruediger et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 53 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Synthesis of functionalized bicyclo[3.2.1]octa-2,6-dienes by thermal rearrangement of substituted 6-<i>exo</i>-(1-alkenyl)bicyclo[3.1.0]hex-2-ene systems

Edward Piers, Grace L. Jung, Edward H. Ruediger · Canadian Journal of Chemistry · 1987 · 39 citations · Full text

Natural Sciences, Chemistry, Catalysis +14

New C-5 substituted pyrrolotriazine dual inhibitors of EGFR and HER2 protein tyrosine kinases

Harold Mastalerz, Ming Chang, Ping Chen et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 38 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15