Concepedia

New C-5 substituted pyrrolotriazine dual inhibitors of EGFR and HER2 protein tyrosine kinases

Harold Mastalerz, Ming Chang, Ping Chen, Pierre Dextraze, Brian E. Fink, Ashvinikumar V. Gavai, Bindu Goyal, Wen-Ching Han, Walter L. Johnson, David R. Langley,

Bioorganic & Medicinal Chemistry Letters · 2007 · 38 citations · 15 references

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15

Evaluation and Reparametrization of the OPLS-AA Force Field for Proteins via Comparison with Accurate Quantum Chemical Calculations on Peptides

George A. Kaminski, Richard A. Friesner, Julian Tirado‐Rives et al. · The Journal of Physical Chemistry B · 2001 · 4.1K citations

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A Unique Structure for Epidermal Growth Factor Receptor Bound to GW572016 (Lapatinib)

Edgar R. Wood, Anne T. Truesdale, Octerloney B. McDonald et al. · Cancer Research · 2004 · 1.1K citations · Full text

, , +14

The effects of the novel, reversible epidermal growth factor receptor/ErbB-2 tyrosine kinase inhibitor, GW2016, on the growth of human normal and tumor-derived cell lines in vitro and in vivo.

David W. Rusnak, Karen Lackey, Karen Affleck et al. · PubMed · 2001 · 738 citations

, , +17

AEE788

Peter Traxler, Peter R. Allegrini, Ralf Brandt et al. · Cancer Research · 2004 · 318 citations

, , +17

1,1′-(azodicarbonyl)dipiperidine-tributylphosphine, a new reagent system for mitsunobu reaction

Tetsuto Tsunoda, Yoshiko Yamamiya, Shô Itô · Tetrahedron Letters · 1993 · 220 citations

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