Karen Affleck

A cellular census of human lungs identifies novel cell states in health and in asthma

Felipe A. Vieira Braga, Gozde Kar, Marijn Berg et al. · Nature Medicine · 2019 · 935 citations · Full text

Asthma, Human Cell, Human Lungs Identifies +12

The effects of the novel, reversible epidermal growth factor receptor/ErbB-2 tyrosine kinase inhibitor, GW2016, on the growth of human normal and tumor-derived cell lines in vitro and in vivo.

David W. Rusnak, Karen Lackey, Karen Affleck et al. · PubMed · 2001 · 737 citations

Pathology, Cell Proliferation, Cell Growth +16

The characterization of novel, dual ErbB-2/EGFR, tyrosine kinase inhibitors: potential therapy for cancer.

David W. Rusnak, Karen Affleck, Stuart Cockerill et al. · PubMed · 2001 · 297 citations

Potential Therapy, Tumor Biology, Oncology +18

hCLCA1 and mCLCA3 Are Secreted Non-integral Membrane Proteins and Therefore Are Not Ion Channels

Adele Gibson, Alan P. Lewis, Karen Affleck et al. · Journal of Biological Chemistry · 2005 · 124 citations · Full text

EGFR blockade by tyrosine kinase inhibitor or monoclonal antibody inhibits growth, directs terminal differentiation and induces apoptosis in the human squamous cell carcinoma HN5.

Helmout Modjtahedi, Karen Affleck, Colin Stubberfield et al. · International Journal of Oncology · 1998 · 82 citations

Tyrosine Kinase, Immunology, Immunotherapy +19